Bibliography Tag: full text available

Bibliography Index

Calafat, 2012

Calafat, A. M.; “The U.S. National Health and Nutrition Examination Survey and human exposure to environmental chemicals;” International Journal of Hygiene and Environmental Health, 2012, 215(2), 99-101; DOI: 10.1016/j.ijheh.2011.08.014.

ABSTRACT:

Researchers are increasingly interested in using human biomonitoring – the measurement of chemicals, their metabolites or specific reaction products in biological specimens/body fluids – for investigating exposure to environmental chemicals. General population human biomonitoring programs are useful for investigating human exposure to environmental chemicals and an important tool for integrating environment and health. One of these programs, the National Health and Nutrition Examination Survey (NHANES), conducted in the United States is designed to collect data on the health and nutritional status of the noninstitutionalized, civilian U.S. population. NHANES includes a physical examination, collecting a detailed medical history, and collecting biological specimens (i.e., blood and urine). These biological specimens can be used to assess exposure to environmental chemicals. NHANES human biomonitoring data can be used to establish reference ranges for selected chemicals, provide exposure data for risk assessment, and monitor exposure trends. FULL TEXT

Linhart et al., 2021

Linhart, Caroline, Panzacchi, Simona, Belpoggi, Fiorella, Clausing, Peter, Zaller, Johann G., & Hertoge, Koen; “Year-round pesticide contamination of public sites near intensively managed agricultural areas in South Tyrol;” Environmental Sciences Europe, 2021, 33(1); DOI: 10.1186/s12302-020-00446-y.

ABSTRACT:

BACKGROUND: In a previous study, we found that 45% of public playgrounds near intensively managed agricultural areas were contaminated with mainly endocrine active pesticide residues in spring. Here, we investigated potential contamination over the course of a year.

METHODS: Residue data were analyzed from 96 grass samples collected in spring, summer, autumn, and winter by the South Tyrolean Medical Service in 19 public playgrounds, four schoolyards, and one marketplace located within intensively managed agricultural landscapes. Samples were analyzed for 281 substances using gas-chromatography and mass-spectrometry.

RESULTS: A total of 32 pesticide residues and one preservative agent were found. Almost all of the sites (96%) were contaminated with at least one residue during the year; in 79% of the sites, more than one residue was found. Among the detected residues, 76% are classified as endocrine active substances, with the highest concentrations of the insecticide chlorpyrifos-methyl (0.71 mg kg−1), the herbicide oxadiazon (0.64 mg kg−1), and the fungicides captan (0.46 mg kg−1) and fluazinam (0.23 mg kg−1). The number of residues, their concentrations, and the proportion of contaminated sites varied across seasons (p < 0.001). Twenty-five residues were found in 83% of the sites in spring (median concentration 0.240 mg kg−1), nine in 79% of the sites in summer (0.092 mg kg−1), three in 50% of the sites in autumn (0.076 mg kg−1), and four in 17% of the sites in winter (0.155 mg kg−1). Playgrounds already examined in 2017 in the previous study, were more often contaminated with multiple pesticide residues in 2018 (p = 0.045).

CONCLUSION: This study confirms previous findings of widespread pesticide contamination of public sites within intensively managed agricultural areas. Moreover, pesticide residues were also found in periods with little or no pesticide application in the field (autumn and winter). It is worrisome that many of the detected residues are endocrine active substances and that some of them (thiacloprid, bupirimate, captan, folpet) are “suspected human carcinogens”, according to EU authorities. Thus, we call for more effective controls of pesticide applications to minimize pesticide drift into public places. FULL TEXT

Lamichhane, 2017

Lamichhane, Jay Ram; “Pesticide use and risk reduction in European farming systems with IPM: An introduction to the special issue;” Crop Protection, 2017, 97, 1-6; DOI: 10.1016/j.cropro.2017.01.017.

ABSTRACT:

Not available.

FULL TEXT

Epstein and Zhang, 2014

Epstein, Lynn, & Zhang, Minghua. (2014). The Impact of Integrated Pest Management Programs on Pesticide Use in California, USA. In R. Peshin & D. Pimentel (Eds.), Integrated Pest Management (pp. 173-200): Springer.

ABSTRACT:

Integrated Pest Management (IPM) is often promoted to farmers as a method that can provide the most economical, sustained disease and pest control, but promoted to the public as a method to reduce agricultural pesticide use. California has a public infrastructure for supporting IPM research and implementation, largely through the University of California IPM program. California’s Department of Pesticide Regulation’s Pesticide Use Reports provide a system to track pesticide use state-wide. In practice, IPM in California is extremely pesticide-dependent, particularly in weed control and in agricultural production systems that rely on soil fumigation, such as strawberries. During our study period between 1993 and 2010, California had a decrease in use of 88 % of the highly-used pesticides listed for regulatory concern for human health. However, most of these pesticides were replaced with other chemicals rather than with non-chemical methods. We feature several case studies that illustrate key issues in California IPM: the limited progress in meeting Montreal Protocol guidelines for methyl bromide phase-out due to critical use exemptions for strawberry producers; a successful IPM program to decrease use of dormant-season organophosphates that are important water pollutants; the increase in use of neonicotinoid insecticides, which might have a role in the current bee colony collapse disorder; and the limited use of all of the commercialized microbial biocontrol agents except for Bacillus thuringiensis. FULL TEXT

Zhang et al., 2019b

Zhang, J., Huang, Y., Reddy, K. N., & Wang, B.; “Assessing crop damage from dicamba on non-dicamba-tolerant soybean by hyperspectral imaging through machine learning;” Pest Management Science, 2019, 75(12), 3260-3272; DOI: 10.1002/ps.5448.

ABSTRACT:

BACKGROUND: Dicamba effectively controls several broadleaf weeds. The off-target drift of dicamba spray or vapor drift can cause severe injury to susceptible crops, including non-dicamba-tolerant crops. In a field experiment, advanced hyperspectral imaging (HSI) was used to study the spectral response of soybean plants to different dicamba rates, and appropriate spectral features and models for assessing the crop damage from dicamba were developed.

RESULTS: In an experiment with six different dicamba rates, an ordinal spectral variation pattern was observed at both 1 week after treatment (WAT) and 3 WAT. The soybean receiving a dicamba rate >/=0.2X exhibited unrecoverable damage. Two recoverability spectral indices (HDRI and HDNI) were developed based on three optimal wavebands. Based on the Jeffries-Matusita distance metric, Spearman correlation analysis and independent t-test for sensitivity to dicamba spray rates, a number of wavebands and classic spectral features were extracted. The models for quantifying dicamba spray levels were established using the machine learning algorithms of naive Bayes, random forest and support vector machine.

CONCLUSIONS: The spectral response of soybean injury caused by dicamba sprays can be clearly captured by HSI. The recoverability spectral indices developed were able to accurately differentiate the recoverable and unrecoverable damage, with an overall accuracy (OA) higher than 90%. The optimal spectral feature sets were identified for characterizing dicamba spray rates under recoverable and unrecoverable situations. The spectral features plus plant height can yield relatively high accuracy under the recoverable situation (OA = 94%). These results can be of practical importance in weed management. (c) 2019 Society of Chemical Industry.

FULL TEXT

Cuyno, 2001

Cuyno, L.; “Economic analysis of environmental benefits of integrated pest management: a Philippine case study;” Agricultural Economics, 2001, 25(2-3), 227-233; DOI: 10.1111/j.1574-0862.2001.tb00203.x.

ABSTRACT:

Health and environmental concerns associated with pesticide use have motivated the development of integrated pest management (IPM) programs around the world. Little empirical work has been completed to estimate the value of the environmental benefits of IPM. This paper provides an approach to evaluate a broad set of such benefits for a vegetable program in the Philippines. Assessments were made of (1) IPM-induced reduction in environmental risks posed by pesticides in onion production in the Central Luzon and (2) willingness to pay to reduce those risks. The latter was based on a contingent valuation (CV) interview survey of 176 farmers. Risks to humans, birds, aquatic species, beneficial insects, and other animals were considered. IPM practices on onions reduced the use of specific pesticides from 25 to 65%, depending on the practice, and the projected adoption of IPM practices varied from 36 to 94%. Estimated economic benefits varied from 231 to 305 pesos per person per cropping season (40 pesos = 1 US$). The aggregate value of environmental benefits for the five villages where the IPM research program was centered was estimated at 150,000 US$ for the 4600 local residents. Assessment of environmental benefits can help in designing public policies and regulations, and in justifying support for publicly funded IPM programs.  FULL TEXT

Baker et al., 2019

Baker, S. E., Serafim, A. B., Morales-Agudelo, P., Vidal, M., Calafat, A. M., & Ospina, M.; “Quantification of DEET and neonicotinoid pesticide biomarkers in human urine by online solid-phase extraction high-performance liquid chromatography-tandem mass spectrometry;” Analytical and Bioanalytical Chemistry, 2019, 411(3), 669-678; DOI: 10.1007/s00216-018-1481-0.

ABSTRACT:

Neonicotinoid insecticides are widely used replacements for organophosphate and carbamate insecticides, but the extent of human exposure is largely unknown. On the other hand, based on urinary concentrations of DEET metabolites, human exposure to N,N-diethyl-m-toluamide (DEET) appears to be widespread. We developed a fast online solid-phase extraction high-performance liquid chromatography-isotope dilution tandem mass spectrometry (HPLC-MS/MS) method to measure in 200 muL of human urine the concentrations of six neonicotinoid biomarkers (acetamiprid, N-desmethyl-acetamiprid, clothianidin, imidacloprid, 5-hydroxy-imidacloprid, thiacloprid), and two DEET biomarkers (3-diethyl-carbamoyl benzoic acid, 3-ethyl-carbamoyl benzoic acid). Limits of detection ranged from 0.01 to 0.1 mug/L, depending on the biomarker. Accuracy ranged from 91 to 116% and precision ranged from 3.7 to 10 %RSD. The presented method can be used to increase our understanding of exposure to neonicotinoid insecticides and DEET, and to evaluate the potential health effects from such exposures.  FULL TEXT

Sheppard et al., 2020

Sheppard, L., McGrew, S., & Fenske, R. A.; “Flawed analysis of an intentional human dosing study and its impact on chlorpyrifos risk assessments;” Environment International, 2020, 143, 105905; DOI: 10.1016/j.envint.2020.105905.

ABSTRACT:

In March 1972, Frederick Coulston and colleagues at the Albany Medical College reported results of an intentional chlorpyrifos dosing study to the study’s sponsor, Dow Chemical Company. Their report concluded that 0.03 mg/kg-day was the chronic no-observed-adverse-effect-level (NOAEL) for chlorpyrifos in humans. We demonstrate here that a proper analysis by the original statistical method should have found a lower NOAEL (0.014 mg/kg-day), and that use of statistical methods first available in 1982 would have shown that even the lowest dose in the study had a significant treatment effect. The original analysis, conducted by Dow-employed statisticians, did not undergo formal peer review; nevertheless, EPA cited the Coulston study as credible research and kept its reported NOAEL as a point of departure for risk assessments throughout much of the 1980’s and 1990’s. During that period, EPA allowed chlorpyrifos to be registered for multiple residential uses that were later cancelled to reduce potential health impacts to children and infants. Had appropriate analyses been employed in the evaluation of this study, it is likely that many of those registered uses of chlorpyrifos would not have been authorized by EPA. This work demonstrates that reliance by pesticide regulators on research results that have not been properly peer-reviewed may needlessly endanger the public. FULL TEXT

Leino et al., 2020

Leino, L., Tall, T., Helander, M., Saloniemi, I., Saikkonen, K., Ruuskanen, S., & Puigbo, P.; “Classification of the glyphosate target enzyme (5-enolpyruvylshikimate-3-phosphate synthase) for assessing sensitivity of organisms to the herbicide;” Journal of Hazardous Materials, 2020, 124556; DOI: 10.1016/j.jhazmat.2020.124556.

ABSTRACT:

Glyphosate is the most common broad-spectrum herbicide. It targets the key enzyme of the shikimate pathway, 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which synthesizes three essential aromatic amino acids (phenylalanine, tyrosine and tryptophan) in plants. Because the shikimate pathway is also found in many prokaryotes and fungi, the widespread use of glyphosate may have unsuspected impacts on the diversity and composition of microbial communities, including the human gut microbiome. Here, we introduce the first bioinformatics method to assess the potential sensitivity of organisms to glyphosate based on the type of EPSPS enzyme. We have precomputed a dataset of EPSPS sequences from thousands of species that will be an invaluable resource to advancing the research field. This novel methodology can classify sequences from nearly 90% of eukaryotes and >80% of prokaryotes. A conservative estimate from our results shows that 54% of species in the core human gut microbiome are sensitive to glyphosate. FULL TEXT

Zhang et al., 2021

Zhang, H., Liu, J., Wang, L., & Zhai, Z.; “Glyphosate escalates horizontal transfer of conjugative plasmid harboring antibiotic resistance genes;” Bioengineered, 2021, 12(1), 63-69; DOI: 10.1080/21655979.2020.1862995.

ABSTRACT:

Glyphosate has been frequently detected in water environments because of the wide use for controlling weed in farm lands and urban areas. Presently, the focus of the majority of studies is placed on the toxicity of glyphosate on humans and animals. However, the effects of glyphosate on horizontal transfer of conjugative plasmid carrying antibiotic resistance gene (ARG) are largely unknown. Here, we explored the ability and potential mechanism of glyphosate for accelerating horizontal transfer of conjugative plasmid-mediated ARG. The results showed that glyphosate can effectively boost horizontal transfer rate of conjugative plasmid carrying ARG. The possible mechanism analysis demonstrated that over-production of reactive oxygen species and reactive nitrogen species effectively regulated expression levels of bacterial outer membrane protein and conjugative transfer-related genes, thereby resulting into elevated horizontal transfer rate of plasmid-mediated ARG. In conclusion, this study casts new understanding into the biological effects of glyphosate on ARG. FULL TEXT

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